15. August 2022

Fully vaccinated Spanish woman infected with Omicron 20 days-post Delta

Madrid: A 31-year-old woman in Spain caught the Omicron an infection simply 20 days after the Delta variant, in what’s claimed to be the shortest recognized hole between infections, in response to researchers.

However, in an analogous case a uncommon breakthrough an infection was reported in a vaccinated 61-year-old Delhi physician in 2021, who contracted the Alpha and Delta variants inside 19 days.

The Spanish woman, who was a healthcare employee, first examined optimistic for the an infection on December 20, 2021, in a PCR take a look at throughout employees screening at her place of job.

She was totally vaccinated and had acquired a booster shot 12 days earlier.

The affected person, who did not develop any signs, self-isolated for 10 days earlier than returning to work.

On January 10, 2022, simply 20 days after first testing optimistic, she developed a cough, fever and felt usually unwell and had undergone one other PCR take a look at which was additionally optimistic.

Whole genome sequencing confirmed that the affected person had been infected by two completely different strains of SARS-CoV-2 — in December it was the Delta variant, and the second in January was the Omicron variant.

“This case highlights the potential of the Omicron variant to evade the previous immunity acquired either from a natural infection with other variants or from vaccines,” mentioned Gemma Recio, of Institut Catala de Salut, Tarragona, Spain.

In different phrases, individuals who have had Covid-19 can not assume they’re protected in opposition to reinfection, even when they’ve been totally vaccinated, Recio added.

However, she mentioned collectively the earlier an infection and vaccination partially defend the affected person in opposition to extreme illness and hospitalisation.

“This case also underscores the need to carry out genomic surveillance of viruses in infections in those who are fully vaccinated and in reinfections. Such monitoring will help detect variants with the ability to partially evade the immune response,” Recio famous.

The case report might be introduced at this yr’s European (*20*) of Clinical Microbiology and Infectious Diseases to be held in Lisbon, Portugal, from April 23-26.

A Delhi physician, Veena Aggarwal was thrice infected with Covid-19 — contracting each the Alpha and Delta variants after vaccination.

Aggarwal first examined optimistic on August 16, 2020, and was asymptomatic. She acquired her first dose of Covishield vaccine on February 1, 2021, adopted by the second dose on March 15, 2021.

On April 12, she examined optimistic for the second time and had signs corresponding to acute belly ache, fever, myalgia and fatigue. Within 19 days, on May 3, she examined optimistic for the third time.

The an infection resulted in hypoxia, hospitalisation and sickness lasting seven weeks. Whole genome sequencing confirmed the second an infection was attributable to the Alpha variant and the third by the Delta variant.

Her case reported within the peer reviewed medical journal Frontiers in Medicine recognized a uncommon breakthrough an infection in 19 days and in addition confirmed it as a reinfection, presenting the primary such documented case of two reinfections and two breakthrough infections.

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